In each section, you can view the visual abstract and project description along with links to the team’s presentation and the full project report.
Our project aims to propose a new treatment method for osteoarthritis. In our project we designed synthetically engineered exosomes that carry the miRNA-140 and deliver it specifically to chondrocytes due to a chondrocyte affinity peptide, stopping the expression of certain cartilage degrading proteins. The whole project is supported by computational simulations for every process.
The aim of our project is to identify and transfect the B. braunii component(s) that composes the lipid exudation system into microalgae with high growth rate. Catalog microalgal genetic elements for the purpose of creating biological parts. To test and validate a laboratory-scale photobioreactor.
In an effort to provide accurate, affordable, and rapid Point of Care (POC) diagnostic tests for COVID-19 and other emerging pandemics, Purdue iGEM has been working on cArgo: a saliva-based diagnostic device with an Argonaute-mediated testing assay that can be reprogrammed to detect any viral pathogen. cArgo's assay includes chitosan RNA extraction, RT-RPA, TtAgo cleavage, and molecular beacons.
Cotton seeds are highly nutritious however they are not recommended for direct consumption due to the presence of toxin gossypol. On direct consumption, free gossypol can cause serious health issues both in humans and animals. Our primary aim is to degossypolize the cottonseed meal (CSM) using a tailor-made enzyme, thereby making cottonseed fit for consumption.
Ollin SynBio IPN
Tetl-Box is a synthetic biology toolbox, a compendium of essential tools in the form of DIY reagents that let students have a safe, affordable, and simple approach to biotechnology, molecular biology, and synthetic biology through a series of lab protocols for DNA extraction, enzymatic digestion, and ligation, cell transformation, biobrick obtention, and PCR.
Our project is focusing on the recycling of waste in Zimbabwe's high density areas and industries, we are aware that there is a poor disposal of wastes. We are mainly focusing on refuse recycling from homesteads and industrial refuse such as plastics into PBH (polyhydroxybutyrate). Our project focuses on turning plastics into PBH and refuse into beneficial products to be used.
We aimed to computationally design and analyze dengue peptide inhibitors and design a genetic circuit to synthesize peptide inhibitors.
Unsupervised discharge of whey water can cause environmental problems. We aim to grow engineered K. xylinus in whey to produce bacterial cellulose (BC). BC can be used to produce insulin patches to address diabetes, a major health risk in India. Constraint based analysis of our strains and modeling of the patch were done. Thus, with value addition to wastewater we get closer to a circular economy.
P(d)PANA is a molecular biology technique based on a bioinformatics approach in which the antigenic regions are selected from coronavirus proteins. With this, recombinant proteins will be generated on the M13 phage envelope. This method turns out to be ideal for mass production and storage at a low cost to improve vaccination efficiencies for emerging economies.